Ontology highlight
ABSTRACT:
SUBMITTER: van Rheede JJ
PROVIDER: S-EPMC9270436 | biostudies-literature | 2022 Jul
REPOSITORIES: biostudies-literature
van Rheede Joram J JJ Feldmann Lucia K LK Busch Johannes L JL Fleming John E JE Mathiopoulou Varvara V Denison Timothy T Sharott Andrew A Kühn Andrea A AA
NPJ Parkinson's disease 20220708 1
Beta-band activity in the subthalamic local field potential (LFP) is correlated with Parkinson's disease (PD) symptom severity and is the therapeutic target of deep brain stimulation (DBS). While beta fluctuations in PD patients are well characterized on shorter timescales, it is not known how beta activity evolves around the diurnal cycle, outside a clinical setting. Here, we obtained chronic recordings (34 ± 13 days) of subthalamic beta power in PD patients implanted with the Percept DBS devic ...[more]