Ontology highlight
ABSTRACT:
SUBMITTER: Deutschmann S
PROVIDER: S-EPMC9299231 | biostudies-literature | 2022 Jan
REPOSITORIES: biostudies-literature
Deutschmann Sabina S Rimle Lukas L von Ballmoos Christoph C
Chembiochem : a European journal of chemical biology 20211124 2
The topological organization of proteins embedded in biological membranes is crucial for the tight interplay between these enzymes and their accessibility to substrates in order to fulfil enzymatic activity. The orientation of a membrane protein reconstituted in artificial membranes depends on many parameters and is hardly predictable. Here, we present a convenient approach to assess this important property independent of the enzymatic activity of the reconstituted protein. Based on cysteine-spe ...[more]