Ontology highlight
ABSTRACT:
SUBMITTER: Blanken D
PROVIDER: S-EPMC7455746 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Blanken Duco D Foschepoth David D Serrão Adriana Calaça AC Danelon Christophe C
Nature communications 20200828 1
Lipid membranes, nucleic acids, proteins, and metabolism are essential for modern cellular life. Synthetic systems emulating the fundamental properties of living cells must therefore be built upon these functional elements. In this work, phospholipid-producing enzymes encoded in a synthetic minigenome are cell-free expressed within liposome compartments. The de novo synthesized metabolic pathway converts precursors into a variety of lipids, including the constituents of the parental liposome. Ba ...[more]