T₂ quantification in brain using 3D fast spin-echo imaging with long echo trains.

ABSTRACT:

Purpose

Three-dimensional fast spin-echo (FSE) sequences commonly use very long echo trains (>64 echoes) and severely reduced refocusing angles. They are increasingly used in brain exams due to high, isotropic resolution and reasonable scan time when using long trains and short interecho spacing. In this study, T₂ quantification in 3D FSE is investigated to achieve increased resolution when comparing with established 2D (proton-density dual-echo and multi-echo spin-echo) methods.

Methods

The FSE sequence design was explored to use long echo trains while minimizing T₂ fitting error and maintaining typical proton density and T₂ -weighted contrasts. Constant and variable flip angle trains were investigated using extended phase graph and Bloch eq

SUBMITTER: Snyder J 

PROVIDER: S-EPMC9299830 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature