Ontology highlight
ABSTRACT:
SUBMITTER: Zuniga L
PROVIDER: S-EPMC9309325 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Zúñiga Leandro L Cayo Angel A González Wendy W Vilos Cristian C Zúñiga Rafael R
OncoTargets and therapy 20220720
Potassium (K<sup>+</sup>) channels are highly regulated membrane proteins that control the potassium ion flux and respond to different cellular stimuli. These ion channels are grouped into three major families, Kv (voltage-gated K<sup>+</sup> channel), Kir (inwardly rectifying K<sup>+</sup> channel) and K2P (two-pore K<sup>+</sup> channels), according to the structure, to mediate the K<sup>+</sup> currents. In cancer, alterations in K<sup>+</sup> channel function can promote the acquisition of t ...[more]