Ontology highlight
ABSTRACT:
SUBMITTER: Stamos JD
PROVIDER: S-EPMC9315604 | biostudies-literature | 2022 Jul
REPOSITORIES: biostudies-literature
Stamos James D JD Lee Lee H LH Taylor Calvin C Elias Tony T Adams Sandra D SD
Microorganisms 20220720 7
About half a billion people worldwide are infected with herpes simplex virus-2 (HSV-2). Prolonged treatment with acyclovir (ACV) and its analogs leads to the development of resistant strains. The aim of this study was to investigate the antiviral potential of epigallocatechin gallate (EGCG) from <i>Camellia sinensis</i> and a stable analog EGCG-stearate (EGCG-S) against HSV-2 in cultured Vero cells. Cell viability and cell proliferation assays were used to determine the non-cytotoxic concentrati ...[more]