Ontology highlight
ABSTRACT:
SUBMITTER: Kim YN
PROVIDER: S-EPMC9316192 | biostudies-literature | 2022 Jul
REPOSITORIES: biostudies-literature
Kim Yoo-Na YN Kim Min Kyu MK Lee Young Joo YJ Lee Youngeun Y Sohn Ji Yeon JY Lee Jung-Yun JY Choi Min Chul MC Kim Migang M Jung Sang Geun SG Joo Won Duk WD Lee Chan C
Cancers 20220713 14
We aimed to investigate the prevalence and relative contributions of LS and non-LS mutations in patients with endometrial cancer in Korea. We retrospectively reviewed the medical records of 204 patients diagnosed with endometrial cancer who underwent a germline next generation sequencing multigene panel test covering MLH1, MSH2, MSH6, PMS2, and EPCAM at three tertiary centers. Thirty patients (14.7%) with pathogenic mutations (12 MLH1; 6 MSH2; 10 MSH6; 2 PMS2) and 20 patients (9.8%) with 22 uncl ...[more]