Evaluation of the Accessibility of Molecules in Hydrogels Using a Scale of Spin Probes.

ABSTRACT: In this work, we explored by means of electron paramagnetic resonance (EPR) spectroscopy the accessibility of a series of spin probes, covering a scale of molecular weights in the range of 200-60,000 Da, in a variety of hydrogels: covalent network, ionotropic, interpenetrating polymer network (IPN) and semi-IPN. The covalent gel network consists of polyethylene or polypropylene chains linked via isocyanate groups with cyclodextrin, and the ionotropic gel is generated by alginate in the presence of Ca²⁺ ions, whereas semi-IPN and IPN gel networks are generated in a solution of alginate and chitosan by adding crosslinking agents, Ca²⁺ for alginate and glutaraldehyde for chitosan. It was observed that the size of the diffusing species determines the ability of the

SUBMITTER: Matei I 

PROVIDER: S-EPMC9316983 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature