Browse
Submit Data
Databases
API
Help

Dataset Information

20 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

A Synergistic Effect of Phthalimide-Substituted Sulfanyl Porphyrazines and Carbon Nanotubes to Improve the Electrocatalytic Detection of Hydrogen Peroxide

ABSTRACT: A sulfanyl porphyrazine derivative with peripheral phthalimide moieties was metallated with cobalt(II) and iron(II) metal ions. The purity of the macrocycles was confirmed by HPLC, and subsequently, compounds were characterized using various analytical methods (ES-TOF, MALDI-TOF, UV–VIS, and NMR spectroscopy). To obtain hybrid electroactive electrode materials, novel porphyrazines were combined with multiwalled carbon nanotubes. The electrocatalytic effect derived from cobalt(II) and iron(II) cations was evaluated. As a result, a significant decrease in the overpotential was observed compared with that obtained with bare glassy carbon (GC) or glassy carbon electrode/carbon nanotubes (GC/MWCNTs), which allowed for sensitive determination of hydrogen peroxide in neutral conditions (pH 7.4). The prepared sensor enables a linear response to H2O2 concentrations of 1–90 µM. A low detection limit of 0.18 μM and a high sensitivity of 640 μA mM−1 cm−2 were obtained. These results indicate that the obtained sensors could potentially be applied in biomedical and environmental fields.

SUBMITTER: Falkowski M

PROVIDER: S-EPMC9322414 | biostudies-literature |

REPOSITORIES: biostudies-literature

ACCESS DATA

Json Xml

Similar Datasets

Synergistic antibacterial activity of silver nanoparticles and hydrogen peroxide.

Project description:The increasing challenge of antibiotic resistance requires not only the discovery of new antibiotics, but also the development of new alternative approaches. Herein, the synergistic antibacterial activity of silver nanoparticles and hydrogen peroxide combination is reported. Unlike the bacteriostatic or slightly bactericidal activity achieved by using each agent alone, using these two agents in combination, even at relatively low concentrations, resulted in complete eradication of both the Gram negative Escherichia coli and the Gram positive Staphylococcus aureus in short treatment times indicating a clear synergistic effect between them. Modifying the surface chemistry of silver nanoparticles and the accompanied change in their surface charge enabled a further enhancement of such synergistic effect implying the importance of this aspect. Mechanistically, a Fenton-like reaction between silver nanoparticles and hydrogen peroxide is discussed and hypothesized to be the basis of the observed synergy. Achieving such a significant antibacterial activity at low concentrations reduces the potential toxicity of these agents and hence enables their utilization as an alternative antibacterial approach in wider range of applications.

| S-EPMC6687290 | biostudies-literature

Tetranuclear Manganese Models of the OEC Displaying Hydrogen Bonding Interactions: Application to Electrocatalytic Water Oxidation to Hydrogen Peroxide.

Project description:Toward the development of structural and functional models of the oxygen evolving complex (OEC) of photosystem II, we report the synthesis of site-differentiated tetranuclear manganese complexes featuring three six-coordinate and one five-coordinate Mn centers. To incorporate biologically relevant second coordination sphere interactions, substituents capable of hydrogen bonding are included as pyrazolates with arylamine substituents. Complexes with terminal anionic ligands, OH- or Cl-, bound to the lower coordinate metal center are supported through the hydrogen-bonding network in a fashion reminiscent of the enzymatic active site. The hydroxide complex was found to be a competent electrocatalyst for O-O bond formation, a key transformation pertinent to the OEC. In an acetonitrile-water mixture, at neutral pH, electrochemical water oxidation to hydrogen peroxide was observed, albeit with low (15%) Faradaic yield, likely due to competing reactions with organics. In agreement, 9,10-dihydroanthracene is electrochemically oxidized in the presence of this cluster both via H-atom abstraction and oxygenation with ?50% combined Faradaic yield.

| S-EPMC5643074 | biostudies-literature

Chronoamperometric Observation and Analysis of Electrocatalytic Ability of Single Pd Nanoparticle for Hydrogen Peroxide Reduction Reaction.

Project description:The current generated by the collision of a single nanoparticle (NP) of palladium (Pd) on a gold (Au) ultramicroelectrode (UME) surface was observed using an electrocatalytic amplification method. The hydrogen peroxide reduction reaction was used for the electrocatalytic reaction because the hydrogen peroxide reduction reaction has no gas-phase product, which would induce rapid signal decay. The electrocatalytic current resulting from a single Pd nanoparticle on the Au UME shows a staircase response with accompanying slow current decay. The applying potential and concentration of hydrogen peroxide were optimized for clear distinction of signal. The height of the current step and signal frequency were analyzed and compared with the theoretical expectation. The analysis of the electrocatalytic activity of single Pd NPs provides insight toward their future application.

| S-EPMC6266670 | biostudies-literature

Biomimetic versus enzymatic high-potential electrocatalytic reduction of hydrogen peroxide on a functionalized carbon nanotube electrode.

Project description:We report the non-covalent functionalization of a multi-walled carbon nanotube (MWCNT) electrode with a biomimetic model of the horseradish peroxidase (HRP) active site. By modifying the MWCNT electrode surface with imidazole-modified polypyrrole, a new biomimetic complex of HRP was synthesized on the MWCNT sidewalls via the coordination of imidazole (Im) to the metal centre of iron protoporphyrin IX, affording (Im)(PP)FeIII . Compared to the pi-stacking of non-coordinated (PP)FeIII on a MWCNT electrode, the (Im)(PP)FeIII -modified MWCNT electrode exhibits higher electrocatalytic activity with an Imax = 0.52 mA cm-2 for the reduction of H2O2, accompanied by a high onset potential of 0.43 V vs. Ag/AgCl. The performances of these novel surface-confined HRP mimics were compared to those of a MWCNT electrode modified by HRP. Although the enzyme electrode displays a higher electrocatalytic activity towards H2O2 reduction, the (Im)(PP)FeIII -modified MWCNT electrode exhibits a markedly higher operational stability, retaining 63% of its initial activity after one month.

| S-EPMC5666682 | biostudies-literature

Photoelectrocatalytic Synthesis of Hydrogen Peroxide by Molecular Copper-Porphyrin Supported on Titanium Dioxide Nanotubes.

Project description:We report on a self-assembled system comprising a molecular copper-porphyrin photoelectrocatalyst, 5-(4-carboxy-phenyl)-10,15,20-triphenylporphyrinatocopper(II) (CuTPP-COOH), covalently bound to self-organized, anodic titania nanotube arrays (TiO2 NTs) for photoelectrochemical reduction of oxygen. Visible light irradiation of the porphyrin-covered TiO2 NTs under cathodic polarization up to -0.3?V vs. Normal hydrogen electrode (NHE) photocatalytically produces H2O2 in pH neutral electrolyte, at room temperature and without need of sacrificial electron donors. The formation of H2O2 upon irradiation is proven and quantified by direct colorimetric detection using 4-nitrophenyl boronic acid (p-NPBA) as a reactant. This simple approach for the attachment of a small molecular catalyst to TiO2 NTs may ultimately allow for the preparation of a low-cost H2O2 evolving cathode for efficient photoelectrochemical energy storage under ambient conditions.

| S-EPMC5947148 | biostudies-literature

Co-axial heterostructures integrating palladium/titanium dioxide with carbon nanotubes for efficient electrocatalytic hydrogen evolution.

Project description:Considering the depletion of fossil-fuel reserves and their negative environmental impact, new energy schemes must point towards alternative ecological processes. Efficient hydrogen evolution from water is one promising route towards a renewable energy economy and sustainable development. Here we show a tridimensional electrocatalytic interface, featuring a hierarchical, co-axial arrangement of a palladium/titanium dioxide layer on functionalized multi-walled carbon nanotubes. The resulting morphology leads to a merging of the conductive nanocarbon core with the active inorganic phase. A mechanistic synergy is envisioned by a cascade of catalytic events promoting water dissociation, hydride formation and hydrogen evolution. The nanohybrid exhibits a performance exceeding that of state-of-the-art electrocatalysts (turnover frequency of 15000 H2 per hour at 50?mV overpotential). The Tafel slope of ?130?mV per decade points to a rate-determining step comprised of water dissociation and formation of hydride. Comparative activities of the isolated components or their physical mixtures demonstrate that the good performance evolves from the synergistic hierarchical structure.

| S-EPMC5159813 | biostudies-other

Adaptation to hydrogen peroxide

Project description:Adaptation to hydrogen peroxide in Saccharomyces cerevisiae is profiled with expression arrays. Adaptation describes the process in which a mild dose of toxin (in this case, hydrogen peroxide) is able to protect against a later acute dose. Here, we study two adaptive protocols (0.1 mM H2O2 and 0.1 + 0.4 mM H2O2) and one acute protocol (0.4 mM H2O2) to identify processes uniquely involved in adaptation. Predictions from these studies are validated in expression profiling of deletion mutants of the transcription factors Yap1, Mga2, and Rox1.

2009-04-23 | GSE12602 | GEO

Sulfanyl Porphyrazines with Morpholinylethyl Periphery-Synthesis, Electrochemistry, and Photocatalytic Studies after Deposition on Titanium(IV) Oxide P25 Nanoparticles.

Project description:The syntheses, spectral UV-Vis, NMR, and electrochemical as well as photocatalytic properties of novel magnesium(II) and zinc(II) symmetrical sulfanyl porphyrazines with 2-(morpholin-4-yl)ethylsulfanyl peripheral substituents are presented. Both porphyrazine derivatives were synthesized in cyclotetramerization reactions and subsequently embedded on the surface of commercially available P25 titanium(IV) oxide nanoparticles. The obtained macrocyclic compounds were broadly characterized by ESI MS spectrometry, 1D and 2D NMR techniques, UV-Vis spectroscopy, and subjected to electrochemical studies. Both hybrid materials, consisting of porphyrazine derivatives embedded on the titanium(IV) oxide nanoparticles' surface, were characterized in terms of particle size and distribution. Next, they were subjected to photocatalytic studies with 1,3-diphenylisobenzofuran, a known singlet oxygen quencher. The applicability of the obtained hybrid material consisting of titanium(IV) oxide P25 nanoparticles and magnesium(II) porphyrazine derivative was assessed in photocatalytic studies with selected active pharmaceutical ingredients, such as diclofenac sodium salt and ibuprofen.

| S-EPMC8071117 | biostudies-literature

Mechanistic Study of the Activation and the Electrocatalytic Reduction of Hydrogen Peroxide by Cu-tmpa in Neutral Aqueous Solution.

Project description:Hydrogen peroxide plays an important role as an intermediate and product in the reduction of dioxygen by copper enzymes and mononuclear copper complexes. The copper(II) tris(2-pyridylmethyl)amine complex (Cu-tmpa) has been shown to produce H2O2 as an intermediate during the electrochemical 4-electron reduction of O2. We investigated the electrochemical hydrogen peroxide reduction reaction (HPRR) by Cu-tmpa in a neutral aqueous solution. The catalytic rate constant of the reaction was shown to be one order of magnitude lower than the reduction of dioxygen. A significant solvent kinetic isotope effect (KIE) of 1.4 to 1.7 was determined for the reduction of H2O2, pointing to a Fenton-like reaction pathway as the likely catalytic mechanism, involving a single copper site that produces an intermediate copper(II) hydroxo species and a free hydroxyl radical anion in the process.

| S-EPMC8453753 | biostudies-literature

Synergistic Regulation of S-Vacancy of MoS<sub>2</sub>-Based Materials for Highly Efficient Electrocatalytic Hydrogen Evolution.

Project description:Low or excessively high concentration of S-vacancy (C S-vacancy) is disadvantageous for the hydrogen evolution reaction (HER) activity of MoS2-based materials. Additionally, alkaline water electrolysis is most likely to be utilized in the industry. Consequently, it is of great importance for fine-tuning C S-vacancy to significantly improve alkaline hydrogen evolution. Herein, we have developed a one-step Ru doping coupled to compositing with CoS2 strategy to precisely regulate C S-vacancy of MoS2-based materials for highly efficient HER. In our strategy, Ru doping favors the heterogeneous nucleation and growth of CoS2, which leads to a high crystallinity of Ru-doped CoS2 (Ru-CoS2) and rich heterogeneous interfaces between Ru-CoS2 and Ru-doped MoS2-x (Ru-MoS2-x). This facilitates the electron transfer from Ru-CoS2 to Ru-MoS2-x, thereby increasing C S-vacancy of MoS2-based materials. Additionally, the electron injection effect increases gradually with an increase in the mass of Co precursor (m Co), which implies more S2- leaching from MoS2 at higher m Co. Subsequently, C S-vacancy of the as-synthesized samples is precisely regulated by the synergistic engineering of Ru doping and compositing with CoS2. At C S-vacancy = 17.1%, a balance between the intrinsic activity and the number of exposed Mo atoms (EMAs) to boost highly active EMAs should be realized. Therefore, the typical samples demonstrate excellent alkaline HER activity, such as a low overpotential of 170 mV at 100 mA cm-2 and a TOF of 4.29 s-1 at -0.2 V. Our results show promise for important applications in the fields of electrocatalysis or energy conversion.

| S-EPMC9214220 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data