Browse
Submit Data
Databases
API
Help

Dataset Information

15 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Surface-Oxidized Polymer-Stabilized Silver Nanoparticles as a Covering Component of Suture Materials

ABSTRACT: In this work, we obtained silver nanoparticles stabilized with polyvinylpyrrolidone, ranging in size from 70 to 110 nm, which exhibits good crystallinity and anisotropic structure. For the first time, we studied the influence of the molar ratio of silver between silver and peroxide on the oxidation process of the nanoparticles and determined the regularities of this process by analyzing changes in absorption spectra. Our results showed that at molar ratios of Ag:H2O2 = 1:1 and 1:5, dependences of changes in the intensity, position and half-width of the absorption band of the plasmon resonance are rectilinear. In vivo studies of silver nanoparticles have shown that silver nanoparticles belong to the toxicity class III (moderately hazardous substance) and to the third group according to the degree of accumulation. We established that silver nanoparticles and oxidized silver nanoparticles form a uniform layer on the surface of the suture material. We found that the use of the suture material with silver nanoparticles and oxidized silver nanoparticles does not cause allergic reactions in the organisms of laboratory animals.

SUBMITTER: Blinov A

PROVIDER: S-EPMC9323226 | biostudies-literature |

REPOSITORIES: biostudies-literature

ACCESS DATA

Json Xml

Similar Datasets

Changes in Number and Antibacterial Activity of Silver Nanoparticles on the Surface of Suture Materials during Cyclic Freezing.

Project description:This article presents the results of the 10-fold cyclic freezing (-37.0 °C) and thawing (0.0 °C) effect on the number and size range of silver nanoparticles (AgNPs). AgNPs were obtained by the cavitation-diffusion photochemical reduction method and their sorption on the fiber surface of various suture materials, perlon, silk, and catgut, was studied. The distribution of nanoparticles of different diameters before and after the application of the cyclic freezing/thawing processes for each type of fibers studied was determined using electron microscopy. In general, the present study demonstrates the effectiveness of using the technique of 10-fold cyclic freezing. It is applicable to increase the absolute amount of AgNPs on the surface of the suture material with a simultaneous decrease in the size dispersion. It was also found that the application of the developed technique leads to the overwhelming predominance of nanoparticles with 1 to 15 nm diameter on all the investigated fibers. In addition, it was shown that after the application of the freeze/thaw method, the antibacterial activity of silk and catgut suture materials with AgNPs was significantly higher than before their treatment by cyclic freezing.

| S-EPMC9000594 | biostudies-literature

Surface Charge-Modulated Toxicity of Cysteine-Stabilized Silver Nanoparticles.

Project description:The toxicity of silver nanoparticles (AgNPs) depends on their physicochemical properties. The ongoing research aims to develop effective methods for modifying AgNPs using molecules that enable control over the processes induced by nanoparticles in both normal and cancerous cells. Application of amino acid-stabilized nanoparticles appears promising, exhibiting tunable electrokinetic properties. Therefore, this study focused on determining the influence of the surface charge of cysteine (CYS)-stabilized AgNPs on their toxicity towards human normal B (COLO-720L) and T (HUT-78) lymphocyte cell lines. CYS-AgNPs were synthesized via the chemical reduction. Transmission electron microcopy (TEM) imaging revealed that they exhibited a quasi-spherical shape with an average size of 18 ± 3 nm. CYS-AgNPs remained stable under mild acidic (pH 4.0) and alkaline (7.4 and 9.0) conditions, with an isoelectric point observed at pH 5.1. Following a 24 h treatment of lymphocytes with CYS-AgNPs, concentration-dependent alterations in cell morphology were observed. Positively charged CYS-AgNPs notably decreased lymphocyte viability. Furthermore, they exhibited grater genotoxicity and more pronounced disruption of biological membranes compared to negatively charged CYZ-AgNPs. Despite both types of AgNPs interacting similarly with fetal bovine serum (FBS) and showing comparable profiles of silver ion release, the biological assays consistently revealed that the positively charged CYS-AgNPs exerted stronger effects at all investigated cellular levels. Although both types of CYS-AgNPs have the same chemical structure in their stabilizing layers, the pH-induced alterations in their surface charge significantly affect their biological activity.

| S-EPMC11314351 | biostudies-literature

Magnetron-sputtered Polytetrafluoroethylene-stabilized Silver Nanoisland Surface for Surface-Enhanced Fluorescence.

Project description:Surface-enhanced fluorescence (SEF) requires the absorption/emission band of the fluorophore, the localized surface plasmon resonance (LSPR) of the nanostructure and the excitation wavelength to fall in the same (or very close) spectral range. In this paper, we monitor the SEF intensity and lifetime dependence of riboflavin (vitamin B2) adsorbed on a spacer-modified Ag substrate with respect to the thickness of the spacer. The substrates were formed by silver nanoislands deposited onto magnetron-sputtered polytetrafluoroethylene (ms-PTFE). The spacer was formed by the ms-PTFE layer with the thickness ranging from ~5 to 25 nm. The riboflavin dissolved in dimethylsulfoxide (DMSO) at a 10 µM concentration forms, at the ms-PTFE surface, a homogeneous layer of adsorbed molecules corresponding to a monomolecular layer. The microspectroscopic measurements of the adsorbed layer were performed through a sessile droplet; our study has shown the advantages and limitations of this approach. Time-resolved fluorescence enabled us to determine the enhanced fluorescence quantum yield due to the shortening of the radiative decay in the vicinity of the plasmonic surface. For the 5 nm ms-PTFE layer possessing the largest (estimated 4×) fluorescence enhancement, the quantum yield was increased 2.3×.

| S-EPMC7221687 | biostudies-literature

Can Differently Stabilized Silver Nanoparticles Modify Calcium Phosphate Precipitation?

Project description:Calcium phosphates (CaPs) composites with silver nanoparticles (AgNPs) attract attention as a possible alternative to conventional approaches to combating orthopedic implant-associated infections. Although precipitation of calcium phosphates at room temperatures was pointed out as an advantageous method for the preparation of various CaP-based biomaterials, to the best of our knowledge, no such study exists for the preparation of CaPs/AgNP composites. Motivated by this lack of data in this study we investigated the influence of AgNPs stabilized with citrate (cit-AgNPs), poly(vinylpyrrolidone) (PVP-AgNPs), and sodium bis(2-ethylhexyl) sulfosuccinate (AOT-AgNPs) in the concentration range 5–25 mg dm−3 on the precipitation of CaPs. The first solid phase to precipitate in the investigated precipitation system was amorphous calcium phosphate (ACP). The effect of AgNPs on ACP stability was significant only in the presence of the highest concentration of AOT-AgNPs. However, in all precipitation systems containing AgNPs, the morphology of ACP was affected, as gel-like precipitates formed in addition to the typical chain-like aggregates of spherical particles. The exact effect depended on the type of AgNPs. After 60 min of reaction time, a mixture of calcium-deficient hydroxyapatite (CaDHA) and a smaller amount of octacalcium phosphate (OCP) formed. PXRD and EPR data point out that the amount of formed OCP decreases with increasing AgNPs concentration. The obtained results showed that AgNPs can modify the precipitation of CaPs and that CaPs properties can be fine-tuned by the choice of stabilizing agent. Furthermore, it was shown that precipitation can be used as a simple and fast method for CaP/AgNPs composites preparation which is of special interest for biomaterials preparation.

| S-EPMC10003846 | biostudies-literature

Interaction of borohydride stabilized silver nanoparticles with sulfur-containing organophosphates.

Project description:Understanding the interactions between nanoparticles and organophosphates is the key to developing cost-effective colorimetric pesticide detection. We have studied the interaction between three different organophosphates containing the P[double bond, length as m-dash]S group and borohydride stabilized silver nanoparticles. Three different organophosphates, namely phorate, chlorpyrifos, and malathion, have been used. The colorimetric changes are corroborated with UV-visible absorption studies along with the change in particle size and zeta potential. This effect persists in the presence of NaCl solution also. The chlorpyrifos and malathion do not show significant interactions with uncapped nanoparticles over time, while phorate undergoes degradation due to the scission of the S-CH2 linkage. A reaction mechanism, wherein a silver and sulfur (Ag→S) complex is formed, which is in agreement with Raman spectroscopic studies is proposed. The orientations of phorate near Ag nanoparticles are discussed from the adsorption energy calculation using density functional theory.

| S-EPMC9041980 | biostudies-literature

Bremen Silver Nanoparticles

Project description:Impact of silver and silver nanoparticles on the structure and functionality of microbial communities in sewage treatment plants

| PRJEB20907 | ENA

Rapid and sensitive detection of uranyl ion with citrate-stabilized silver nanoparticles by the surface-enhanced Raman scattering technique.

Project description:Uranium contamination poses a huge threat to human health due to its widespread use in the nuclear industry and weapons. We proposed a simple and convenient wet-state SERS method for uranyl detection based on the citrate-stabilized silver nanoparticles. The effect of citrate on the detection performance was also discussed. By using the citrate as an internal reference to normalize the peak of uranyl, a quantitative analysis was achieved and a good linear relationship of uranyl concentration from 0.2 to 5 µM with the limit of detection of 60 nM was obtained. With its simplicity, convenience and cost-effectiveness, this method has great potential for the detection of other molecules also.

| S-EPMC6281930 | biostudies-literature

Site-specific conjugation of antifreeze proteins onto polymer-stabilized nanoparticles.

Project description:Antifreeze proteins (AFPs) have many potential applications, ranging from cryobiology to aerospace, if they can be incorporated into materials. Here, a range of engineered AFP mutants were prepared and site-specifically conjugated onto RAFT polymer-stabilized gold nanoparticles to generate new hybrid multivalent ice growth inhibitors. Only the SNAP-tagged AFPs lead to potent 'antifreeze' active nanomaterials with His-Tag capture resulting in no activity, showing the mode of conjugation is essential. This versatile strategy will enable the development of multivalent AFPs for translational and fundamental studies.

| S-EPMC6592154 | biostudies-literature

Synthesis and Catalytic Activity of Pluronic Stabilized Silver-Gold Bimetallic Nanoparticles.

Project description:In this report, we demonstrate a rapid, simple, and green method for synthesizing silver-gold (Ag-Au) bimetallic nanoparticles (BNPs). We used a novel modification to the galvanic replacement reaction by suspending maltose coated silver nanoparticles (NPs) in ? 2% aqueous solution of EO100PO65EO100 (Pluronic F127) prior to HAuCl4 addition. The Pluronic F127 stabilizes the BNPs, imparts biocompatibility, and mitigates the toxicity issues associated with other surfactant stabilizers. BNPs with higher Au:Ag ratios and, subsequently, different morphologies were successfully synthesized by increasing the concentration of gold salt added to the Ag NP seeds. These BNPs have enhanced catalytic activities than typically reported for monometallic Au or Ag NPs (? 2-10 fold) of comparable sizes in the sodium borohydride reduction of 4-nitrophenol. The 4-nitrophenol reduction rates were highest for partially hollow BNP morphologies.

| S-EPMC4286189 | biostudies-literature

Polyoxometalate-Stabilized Silver Nanoparticles and Hybrid Electrode Assembly Using Activated Carbon.

Project description:The intersection between the field of hybrid materials and that of electrochemistry is a quickly expanding area. Hybrid combinations usually consist of two constituents, but new routes toward more complex and versatile electroactive hybrid designs are quickly emerging. The objective of the present work is to explore novel triple hybrid material integrating polyoxometalates (POMs), silver nanoparticles (Ag0 NPs), and activated carbon (AC) and to demonstrate its use as a hybrid electrode in a symmetric supercapacitor. The tri-component nanohybrid (AC/POM-Ag0 NPs) was fabricated through the combination of AC with pre-synthesized ∼27 nm POM-protected Ag0 NPs (POM-Ag0 NPs). The POM-Ag0 NPs were prepared using a green electrochemical method and characterized via UV-vis and IR spectroscopy, electron microscopy, dynamic light scattering (DLS), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), and cyclic voltammetry (CV). Afterward, the AC/POM-Ag0 NPs ternary nanocomposite material was constructed and characterized. The electrochemical behavior of AC/POM-Ag0 NPs' modified electrodes reveal that the nanomaterial is electroactive and exhibits a moderately higher specific capacitance (81 F/g after 20 cycles) than bare AC electrodes (75 F/g) in a symmetrical supercapacitor configuration in the voltage range 0 to 0.75 V and 20 mV/s, demonstrating the potential use of this type of tri-component nanohybrid for electrochemical applications.

| S-EPMC10421052 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data