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Factors Associated with White Fat Browning: New Regulators of Lipid Metabolism.

ABSTRACT: Mammalian adipose tissue can be divided into white and brown adipose tissue based on its colour, location, and cellular structure. Certain conditions, such as sympathetic nerve excitement, can induce the white adipose adipocytes into a new type of adipocytes, known as beige adipocytes. The process, leading to the conversion of white adipocytes into beige adipocytes, is called white fat browning. The dynamic balance between white and beige adipocytes is closely related to the body's metabolic homeostasis. Studying the signal transduction pathways of the white fat browning might provide novel ideas for the treatment of obesity and alleviation of obesity-related glucose and lipid metabolism disorders. This article aimed to provide an overview of recent advances in understanding white fat browning and the role of BAT in lipid metabolism.

SUBMITTER: Zhang P

PROVIDER: S-EPMC9325132 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature

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Factors Associated with White Fat Browning: New Regulators of Lipid Metabolism.

Zhang Peiwen P He Yuxu Y Wu Shuang S Li Xinrong X Lin Xutao X Gan Mailin M Chen Lei L Zhao Ye Y Niu Lili L Zhang Shunhua S Li Xuewei X Zhu Li L Shen Linyuan L

International journal of molecular sciences 20220711 14

Mammalian adipose tissue can be divided into white and brown adipose tissue based on its colour, location, and cellular structure. Certain conditions, such as sympathetic nerve excitement, can induce the white adipose adipocytes into a new type of adipocytes, known as beige adipocytes. The process, leading to the conversion of white adipocytes into beige adipocytes, is called white fat browning. The dynamic balance between white and beige adipocytes is closely related to the body's metabolic hom ...[more]

PMID: 35886989

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Project description:This SuperSeries is composed of the SubSeries listed below.

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