Ontology highlight
ABSTRACT:
SUBMITTER: Rosenson RS
PROVIDER: S-EPMC9327673 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
Journal of the American College of Cardiology 20211101 18
Emerging evidence suggests that elevated concentrations of triglyceride-rich lipoprotein remnants (TRLs) derived from hepatic and intestinal sources contribute to the risk of atherosclerotic cardiovascular events. Natural selection studies support a causal role for elevated concentrations of remnant cholesterol and the pathways contributing to perturbations in metabolic pathways regulating TRLs with an increased risk of atherosclerotic cardiovascular disease events. New therapies targeting selec ...[more]