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Genome sequence of the aurodox-producing bacterium Streptomyces goldiniensis ATCC 21386.

ABSTRACT: We report the genome sequence of Streptomyces goldiniensis ATCC 21386, a strain which produces the anti-bacterial and anti-virulence polyketide, aurodox. The genome of S. goldiniensis ATCC 21386 was sequenced using a multiplatform hybrid approach, revealing a linear genome of ~10 Mbp with a G+C content of 71%. The genome sequence revealed 36 putative biosynthetic gene clusters (BGCs), including a large region of 271 Kbp that was rich in biosynthetic capability. The genome sequence is deposited in DDBJ/EMBL/GenBank with the accession number PRJNA602141.

SUBMITTER: McHugh RE 

PROVIDER: S-EPMC9394534 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature

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Genome sequence of the aurodox-producing bacterium <i>Streptomyces goldiniensis</i> ATCC 21386.

McHugh Rebecca E RE   Munnoch John T JT   Roe Andrew J AJ   Hoskisson Paul A PA  

Access microbiology 20220819 5

We report the genome sequence of <i>Streptomyces goldiniensis</i> ATCC 21386, a strain which produces the anti-bacterial and anti-virulence polyketide, aurodox. The genome of <i>S. goldiniensis</i> ATCC 21386 was sequenced using a multiplatform hybrid approach, revealing a linear genome of ~10 Mbp with a G+C content of 71%. The genome sequence revealed 36 putative biosynthetic gene clusters (BGCs), including a large region of 271 Kbp that was rich in biosynthetic capability. The genome sequence  ...[more]

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