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A new class of cobalamin transport mutants (btuF) provides genetic evidence for a periplasmic binding protein in Salmonella typhimurium.


ABSTRACT: No periplasmic binding protein has been demonstrated for the ATP-binding cassette (ABC)-type cobalamin transporter BtuCD. New mutations (btuF) are described that affect inner-membrane transport. The BtuF protein has a signal sequence and resembles the periplasmic binding proteins of several other ABC transporters.

SUBMITTER: Van Bibber M 

PROVIDER: S-EPMC94070 | biostudies-literature | 1999 Sep

REPOSITORIES: biostudies-literature

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A new class of cobalamin transport mutants (btuF) provides genetic evidence for a periplasmic binding protein in Salmonella typhimurium.

Van Bibber M M   Bradbeer C C   Clark N N   Roth J R JR  

Journal of bacteriology 19990901 17


No periplasmic binding protein has been demonstrated for the ATP-binding cassette (ABC)-type cobalamin transporter BtuCD. New mutations (btuF) are described that affect inner-membrane transport. The BtuF protein has a signal sequence and resembles the periplasmic binding proteins of several other ABC transporters. ...[more]

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