GPX8 as a Novel Prognostic Factor and Potential Therapeutic Target in Primary Glioma.
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ABSTRACT:
SUBMITTER: Yang ZS
PROVIDER: S-EPMC9427289 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Publications
GPX8 as a Novel Prognostic Factor and Potential Therapeutic Target in Primary Glioma.
Yang Zhao-Shou ZS Yang Qin Q Sun Xiao-Xiao XX Xiong Kui K Zhu Xiao-Ting XT Wang Yi-Chen YC Ren Qian-Yao QY Wu Guo-Hui GH Wang Shi-Min SM Cao Xu-Qin XQ Yang Xiao-Rong XR Jiang Wen-Gong WG
Journal of immunology research 20220823
One of the most prevalent malignant primary brain tumors is primary glioma. Although glutathione peroxidase 8 (GPX8) is intimately associated with carcinogenesis, its function in primary gliomas has not yet been thoroughly understood. Here, we leveraged Chinese Glioma Genome Atlas (CGGA), The Cancer Genome Atlas (TCGA), and Genotype-Tissue Expression (GTEx) database to investigate the association between GPX8 and overall survival (OS) of patients with primary gliomas, and our results showed that ...[more]
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