Ontology highlight
ABSTRACT:
SUBMITTER: Lee E
PROVIDER: S-EPMC9430440 | biostudies-literature | 2022 Aug
REPOSITORIES: biostudies-literature
Lee Euihyun E Baiz Carlos R CR
Chemical science 20220808 34
Dimethyl sulfoxide (DMSO) increases cell and tissue viability at low temperatures and is commonly used as a cryoprotectant for cryogenic storage of biological materials. DMSO disorders the water hydrogen-bond networks and inhibits ice-crystal growth, though the specific DMSO interactions with water are difficult to characterize. In this study, we use a combination of Fourier Transform infrared spectroscopy (FTIR), molecular dynamics simulations, and vibrational frequency maps to characterize the ...[more]