Disruption of aldA influences the developmental process in Myxococcus xanthus.
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ABSTRACT:
SUBMITTER: Ward MJ
PROVIDER: S-EPMC94313 | biostudies-literature | 2000 Jan
REPOSITORIES: biostudies-literature
Publications
Disruption of aldA influences the developmental process in Myxococcus xanthus.
Ward M J MJ Lew H H Zusman D R DR
Journal of bacteriology 20000101 2
Previously, we identified a gene (aldA) from Myxococcus xanthus, which we suggested encoded the enzyme alanine dehydrogenase on the basis of similarity to known Ald protein sequences (M. J. Ward, H. Lew, A. Treuner-Lange, and D. R. Zusman, J. Bacteriol. 180:5668-5675, 1998). In this study, we have confirmed that aldA does encode a functional alanine dehydrogenase, since it catalyzes the reversible conversion of alanine to pyruvate and ammonia. Whereas an aldA gene disruption mutation did not sig ...[more]
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