Ontology highlight
ABSTRACT:
SUBMITTER: Monteiro A
PROVIDER: S-EPMC9437773 | biostudies-literature | 2022 Oct
REPOSITORIES: biostudies-literature
Monteiro Ajit A Chang Arthur J AJ Welliver R Ross RR Baron Sarah S Hicar Mark D MD
Virology 20220902
Multisystem Inflammatory Syndrome in Children (MIS-C), a post infectious complication of SARS CoV-2 infection, shares enough features with Kawasaki Disease (KD) that some have hypothesized cross-coronavirus (CoV) immunity may explain the shared pathology. Recent studies have shown that humoral cross-reactivity of the CoVs, particularly of OC43, is focused on the S2 region of the Spike protein. Due to efforts utilizing CoV S2 regions to produce a cross-CoV vaccine, we wished to assess SARS-CoV-2 ...[more]