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Paeoniflorin in Paeoniaceae: Distribution, influencing factors, and biosynthesis.


ABSTRACT: Paeoniflorin, a monoterpene glucoside, is increasingly used in the clinical treatment of many diseases because it has a variety of pharmacological activities. Besides, paeoniflorin has been considered the characteristic chemical constituent of Paeoniaceae plants since it was first reported in 1963. Therefore, how to better develop and utilize paeoniflorin in Paeoniaceae has always been a research hotspot. We reviewed the current knowledge on paeoniflorin in Paeoniaceae, with particular emphasis on its distribution and influencing factors. Moreover, the limited understanding of the biosynthesis pathway has restricted the production of paeoniflorin by synthetic biology. This review provides insights into the post-modification pathway of paeoniflorin biosynthesis and proposes directions for further analysis in the future.

SUBMITTER: Zhang XX 

PROVIDER: S-EPMC9478390 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature

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Paeoniflorin in Paeoniaceae: Distribution, influencing factors, and biosynthesis.

Zhang Xiao-Xiao XX   Zuo Jia-Qi JQ   Wang Yi-Ting YT   Duan Hui-Yun HY   Yuan Jun-Hui JH   Hu Yong-Hong YH  

Frontiers in plant science 20220902


Paeoniflorin, a monoterpene glucoside, is increasingly used in the clinical treatment of many diseases because it has a variety of pharmacological activities. Besides, paeoniflorin has been considered the characteristic chemical constituent of Paeoniaceae plants since it was first reported in 1963. Therefore, how to better develop and utilize paeoniflorin in Paeoniaceae has always been a research hotspot. We reviewed the current knowledge on paeoniflorin in Paeoniaceae, with particular emphasis  ...[more]

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