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Case series of transcatherter edge-to-edge repair using MitraClip system with Impella® mechanical circulatory support.


ABSTRACT:

Background

Secondary mitral regurgitation (SMR) is a major comorbidity in patients with heart failure with reduced ejection fraction (HFrEF). Transcatheter edge-to-edge repair (TEER) using the MitraClip™ system is a promising tool for selected patients with SMR and HFrEF. Durable success using this system in patients who have advanced heart failure and unsuitable anatomy remains a clinical challenge.

Case summary

Three patients aged 67-72 years with HFrEF on inotropic support successfully underwent Impella®-assisted TEER at our centre. Following the procedure, two patients were able to be weaned off inotropic support and were discharged, while one patient expired during the index hospitalization.

Discussion

Impella®-assisted TEER may be a feasible strategy for patients with SMR and HFrEF with unstable haemodynamics particularly when cardiac replacement therapy is not applicable.

SUBMITTER: Tanaka S 

PROVIDER: S-EPMC9487902 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature

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Publications

Case series of transcatherter edge-to-edge repair using MitraClip<sup>™</sup> system with Impella<sup>®</sup> mechanical circulatory support.

Tanaka Shuhei S   Imamura Teruhiko T   Narang Nikhil N   Fukuo Atsuko A   Nakamura Makiko M   Fukuda Nobuyuki N   Ueno Hiroshi H   Kinugawa Koichiro K  

European heart journal. Case reports 20220907 9


<h4>Background</h4>Secondary mitral regurgitation (SMR) is a major comorbidity in patients with heart failure with reduced ejection fraction (HFrEF). Transcatheter edge-to-edge repair (TEER) using the MitraClip™ system is a promising tool for selected patients with SMR and HFrEF. Durable success using this system in patients who have advanced heart failure and unsuitable anatomy remains a clinical challenge.<h4>Case summary</h4>Three patients aged 67-72 years with HFrEF on inotropic support succ  ...[more]

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