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ABSTRACT: Background
Secondary mitral regurgitation (SMR) is a major comorbidity in patients with heart failure with reduced ejection fraction (HFrEF). Transcatheter edge-to-edge repair (TEER) using the MitraClip™ system is a promising tool for selected patients with SMR and HFrEF. Durable success using this system in patients who have advanced heart failure and unsuitable anatomy remains a clinical challenge.Case summary
Three patients aged 67-72 years with HFrEF on inotropic support successfully underwent Impella®-assisted TEER at our centre. Following the procedure, two patients were able to be weaned off inotropic support and were discharged, while one patient expired during the index hospitalization.Discussion
Impella®-assisted TEER may be a feasible strategy for patients with SMR and HFrEF with unstable haemodynamics particularly when cardiac replacement therapy is not applicable.
SUBMITTER: Tanaka S
PROVIDER: S-EPMC9487902 | biostudies-literature | 2022 Sep
REPOSITORIES: biostudies-literature
Tanaka Shuhei S Imamura Teruhiko T Narang Nikhil N Fukuo Atsuko A Nakamura Makiko M Fukuda Nobuyuki N Ueno Hiroshi H Kinugawa Koichiro K
European heart journal. Case reports 20220907 9
<h4>Background</h4>Secondary mitral regurgitation (SMR) is a major comorbidity in patients with heart failure with reduced ejection fraction (HFrEF). Transcatheter edge-to-edge repair (TEER) using the MitraClip™ system is a promising tool for selected patients with SMR and HFrEF. Durable success using this system in patients who have advanced heart failure and unsuitable anatomy remains a clinical challenge.<h4>Case summary</h4>Three patients aged 67-72 years with HFrEF on inotropic support succ ...[more]