Ontology highlight
ABSTRACT:
SUBMITTER: Totten AH
PROVIDER: S-EPMC9522676 | biostudies-literature | 2022 Sep
REPOSITORIES: biostudies-literature
Totten Arthur H AH Uzel Gulbu G Khil Pavel P PP Youn Jung-Ho JH Treat Jennifer J Soutar Craig D CD Holland Steven M SM Dekker John P JP Zerbe Christa S CS
Open forum infectious diseases 20220912 9
<i>Mycoplasma orale</i> is a rare cause of invasive infection in immunodeficient hosts. Phosphatidylinositol 3-kinase, regulatory subunit 1 (<i>PI3KR1</i>) mutations predispose patients to sinopulmonary infections, alongside bronchiectasis autoimmunity and lymphoproliferation. We report 2 cases of <i>PI3KR1</i> deficiency with invasive <i>M orale</i> and effective treatment options. ...[more]