Ontology highlight
ABSTRACT:
SUBMITTER: Wagner R
PROVIDER: S-EPMC95330 | biostudies-literature | 2001 Jul
REPOSITORIES: biostudies-literature
Wagner R R Straub M L ML Souciet J L JL Potier S S de Montigny J J
Journal of bacteriology 20010701 14
The FCY2 gene of Saccharomyces cerevisiae encodes a purine-cytosine permease (PCP) that mediates the active transport of purines and cytosine. A structure-function model for this PCP has been recently proposed. In this study, we developed a plasmid-based system that generated a number of affinity-mutated alleles, enabling us to define new amino acids critical for permease function. ...[more]