Ontology highlight
ABSTRACT:
SUBMITTER: Lee CC
PROVIDER: S-EPMC9540607 | biostudies-literature | 2022 May
REPOSITORIES: biostudies-literature
Lee Chi Chung CC Kang Wonchull W Jasniewski Andrew J AJ Stiebritz Martin T MT Tanifuji Kazuki K Ribbe Markus W MW Hu Yilin Y
Nature catalysis 20220516 5
The Mo-nitrogenase catalyses the ambient reduction of N<sub>2</sub> to NH<sub>3</sub> at the M-cluster, a complex cofactor that comprises two metal-sulphur partial cubanes ligated by an interstitial carbide and three belt-sulphurs. A recent crystallographic study suggests binding of N<sub>2</sub> via displacement of the belt-sulphur(s) of the M-cluster upon turnover. However, the direct proof of N<sub>2</sub> binding and belt-sulphur mobilization during catalysis remains elusive. Here we show th ...[more]