Ontology highlight
ABSTRACT:
SUBMITTER: Sun GY
PROVIDER: S-EPMC9555299 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
Sun Grace Y GY Appenteng Michael K MK Li Runting R Woo Taeseon T Yang Bo B Qin Chao C Pan Meixia M Cieślik Magdalena M Cui Jiankun J Fritsche Kevin L KL Gu Zezong Z Will Matthew M Beversdorf David D Adamczyk Agata A Han Xianlin X Greenlief C Michael CM
Neuromolecular medicine 20200914 1
The abundance of docosahexaenoic acid (DHA) in phospholipids in the brain and retina has generated interest to search for its role in mediating neurological functions. Besides the source of many oxylipins with pro-resolving properties, DHA also undergoes peroxidation, producing 4-hydroxyhexenal (4-HHE), although its function remains elusive. Despite wide dietary consumption, whether supplementation of DHA may alter the peroxidation products and their relationship to phospholipid species in brain ...[more]