Serological diagnosis of human cysticercosis by use of recombinant antigens from Taenia solium cysticerci.
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ABSTRACT:
SUBMITTER: Hubert K
PROVIDER: S-EPMC95711 | biostudies-literature | 1999 Jul
REPOSITORIES: biostudies-literature
Publications
Serological diagnosis of human cysticercosis by use of recombinant antigens from Taenia solium cysticerci.
Hubert K K Andriantsimahavandy A A Michault A A Frosch M M Mühlschlegel F A FA
Clinical and diagnostic laboratory immunology 19990701 4
A Taenia solium metacestode cDNA expression library in the lambda ZAPII vector was screened with pooled sera from patients with neurocysticercosis. Sixty primary clones were identified and shown to belong to two classes. The clones NC-3 and NC-9 did not reveal any significant homologies to sequences deposited in the databases and were further characterized. Both recombinant antigens were expressed as glutathione S-transferase fusion proteins and applied for serological diagnosis of human cystice ...[more]
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