Ontology highlight
ABSTRACT:
SUBMITTER: Kouzmitcheva GA
PROVIDER: S-EPMC96025 | biostudies-literature | 2001 Jan
REPOSITORIES: biostudies-literature
Kouzmitcheva G A GA Petrenko V A VA Smith G P GP
Clinical and diagnostic laboratory immunology 20010101 1
Serum antibodies from patients with Lyme disease (LD) were used to affinity select peptide epitopes from 12 large random peptide libraries in phage display format. The selected peptides were surveyed for reactivity with a panel of positive sera (from LD patients) and negative sera (from subjects without LD), thus identifying 17 peptides with a diagnostically useful binding pattern: reactivity with at least three positive sera and no reactivity with any of the negative sera. The peptides define e ...[more]