Ontology highlight
ABSTRACT:
SUBMITTER: Sabalza M
PROVIDER: S-EPMC5755560 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Sabalza Maite M Barber Cheryl A CA Abrams William R WR Montagna Richard R Malamud Daniel D
Journal of visualized experiments : JoVE 20171212 130
High-density peptide microarrays allow screening of more than six thousand peptides on a single standard microscopy slide. This method can be applied for drug discovery, therapeutic target identification, and developing of diagnostics. Here, we present a protocol to discover specific Zika virus (ZIKV) diagnostic peptides using a high-density peptide microarray. A human serum sample validated for ZIKV infection was incubated with a high-density peptide microarray containing the entire ZIKV protei ...[more]