Ontology highlight
ABSTRACT:
SUBMITTER: Pasini EM
PROVIDER: S-EPMC9612615 | biostudies-literature | 2022 Oct
REPOSITORIES: biostudies-literature
Pasini Erica M EM van der Wel Annemarie Voorberg AV Heijmans Nicole N Klop Onny O Zeeman Anne-Marie AM Oostermeijer Herman H Nieuwenhuis Ivonne I Garcia Roberto Rodriguez RR van der Werff Nicole Onur NO Hofman Sam O SO Verreck Frank A W FAW Remarque Edmond J EJ Faber Bart W BW Kocken Clemens H M CHM
NPJ vaccines 20221027 1
Vaccine development for Plasmodium vivax, an important human relapsing malaria, is lagging behind. In the case of the most deadly human malaria P. falciparum, unprecedented high levels of protection have been obtained by immunization with live sporozoites under accompanying chemoprophylaxis, which prevents the onset of blood-stage malaria. Such an approach has not been fully evaluated for relapsing malaria. Here, in the P. cynomolgi-rhesus macaque model for relapsing malaria, we employ the paras ...[more]