Ontology highlight
ABSTRACT:
SUBMITTER: Faber JW
PROVIDER: S-EPMC9636041 | biostudies-literature | 2022 Nov
REPOSITORIES: biostudies-literature
iScience 20221017 11
Trabecular myocardium makes up most of the ventricular wall of the human embryo. A process of compaction in the fetal period presumably changes ventricular wall morphology by converting ostensibly weaker trabecular myocardium into stronger compact myocardium. Using developmental series of embryonic and fetal humans, mice and chickens, we show ventricular morphogenesis is driven by differential rates of growth of trabecular and compact layers rather than a process of compaction. In mouse, fetal c ...[more]