Ontology highlight
ABSTRACT:
SUBMITTER: Shamova O
PROVIDER: S-EPMC96712 | biostudies-literature | 1999 Aug
REPOSITORIES: biostudies-literature
Infection and immunity 19990801 8
We purified three proline-rich antimicrobial peptides from elastase-treated extracts of sheep and goat leukocytes and subjected two of them, OaBac5alpha and ChBac5, to detailed analysis. OaBac5alpha and ChBac5 were homologous to each other and to bovine Bac5. Both exhibited potent, broad-spectrum antimicrobial activity under low-concentration salt conditions. While the peptides remained active against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, and Listeria monocytogenes in 100 ...[more]