Ontology highlight
ABSTRACT:
SUBMITTER: Ippolito A
PROVIDER: S-EPMC9703008 | biostudies-literature | 2022 Nov
REPOSITORIES: biostudies-literature
Ippolito Alberto A Deshpande Vikram S VS
Biophysical journal 20220824 22
Cell-cell interaction dictates cell morphology and organization, which play a crucial role in the micro-architecture of tissues that guides their biological and mechanical functioning. Here, we investigate the effect of cell density on the responses of cells seeded on flat substrates using a novel statistical thermodynamics framework. The framework recognizes the existence of nonthermal fluctuations in cellular response and thereby naturally captures entropic interactions between cells in monola ...[more]