Dataset Information

Retrospective observational analysis of a coronary artery bypass grafting surgery patient cohort: Off-pump versus on-pump.

ABSTRACT:

Objectives

To determine whether surgical technique has an effect on prognosis in coronary artery bypass grafting (CABG).

Design

Retrospective observational.

Setting

Single center.

Participants

All the off-pump (OPCABG) and on-pump (ONCABG) patients at Turku University Central Hospital in 2018.

Interventions

None.

Measurements and main results

After propensity score matching, perioperative, 1-year and 3-year mortality did not differ between the groups. The ONCABG patients received more allogenic red blood cells (1.3 vs. 0.6 units, p = 0.020), autologous red blood cells (564 vs. 285 ml, p < 0.001) and crystalloids (3388 vs. 2808 ml, p < 0.001), and had higher postoperative values of troponin T (581 vs. 222, p = 0.001) and lactate (1.69 vs. 1.23, p < 0.001) than the OPCABG patients.

Conclusions

The both techniques seem equally safe. However, there may be some benefits to avoiding using a heart-lung machine, such as lower infused fluid volumes. Myocardial damage may also be milder and postoperative hemodynamics more balanced in OPCABG patients, based on lower levels of troponin T and lactate.

SUBMITTER: Rantanen M

PROVIDER: S-EPMC9758289 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature

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Publications

Retrospective observational analysis of a coronary artery bypass grafting surgery patient cohort: Off-pump versus on-pump.

Rantanen Matias M Yousif Rizgar R Kallioinen Minna M Hynninen Ville-Veikko VV Peltoniemi Marko M Söderholm Oki O Saarikoski Tuukka T Anttila Vesa V Aittokallio Jenni J

Annals of medicine and surgery (2012) 20221109

<h4>Objectives</h4>To determine whether surgical technique has an effect on prognosis in coronary artery bypass grafting (CABG).<h4>Design</h4>Retrospective observational.<h4>Setting</h4>Single center.<h4>Participants</h4>All the off-pump (OPCABG) and on-pump (ONCABG) patients at Turku University Central Hospital in 2018.<h4>Interventions</h4>None.<h4>Measurements and main results</h4>After propensity score matching, perioperative, 1-year and 3-year mortality did not differ between the groups. T ...[more]

PMID: 36536727

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Project description:BackgroundThis study aims to compare the operative and postoperative results of on-pump (ONCAB) and off-pump (OPCAB) coronary artery bypass surgery (CABG) for multi-vessel coronary revascularization (≥4 anastomoses).MethodsFrom May 2018 to August 2019, a total of 120 patients (22.5% women, mean age 61.5±8.4 years) received either ONCAB (Group 1, n=60) or OPCAB (Group 2, n=60) for multi-vessel coronary artery disease (CAD). Preoperative left ventricular (LV) ejection fraction (EF) was 53.1%±8.4%. Median EuroSCORE II was 1.59 (interquartile range, 1.01-2.54). The median number of performed coronary anastomoses was 4 (interquartile range, 4-5), with equal distribution in both groups (P=0.4). All procedures were performed by highly experienced surgeons. The primary endpoints were overall survival at 30 days and freedom from severe adverse events (SAE), which included myocardial infarction (MI), coronary artery re-operation, and re-thoracotomy, caused by bleeding and stroke.ResultsThe overall survival in both groups was 100% with no intraoperative OPCAB-to-on-pump conversion. The median procedure time was 169 min (interquartile range, 150-179 min) for Group 1 and 183 min (interquartile range, 169-205 min) for Group 2 (P<0.001). The overall freedom from SAE numbered 93.3% (98.3% vs. 88.3%, P=0.030). Postoperative MI rate was 2.5% (n=3) with no significant difference for either group (0 vs. 5.0%, P=0.100). One MI patient underwent a re-operation, and two other patients received a conservative treatment. A total of 2.5% (n=3) of patients underwent a re-thoracotomy on account of bleeding (0 vs. 5.0%, P=0.100); no anastomosis-related bleeding was detected. Blood transfusion was applied in 31.7% of patients (38.3% vs. 25.0%, P=0.090). A total of 1.7% of patients (1.7% vs. 1.7%, P=0.800) developed a stroke. Ventilation time, intensive care unit stay, and hospital stay were similar in both groups.ConclusionsONCAB showed superior freedom from SAE and shorter procedure times when compared to OPCAB for multi-vessel coronary artery revascularization.

Dataset Information

Retrospective observational analysis of a coronary artery bypass grafting surgery patient cohort: Off-pump versus on-pump.

Objectives

Design

Setting

Participants

Interventions

Measurements and main results

Conclusions

Publications

Retrospective observational analysis of a coronary artery bypass grafting surgery patient cohort: Off-pump versus on-pump.

Similar Datasets

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