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SARS-CoV-2 Omicron BA.5 Infections in Vaccinated Persons, Rural Uganda.

ABSTRACT: We describe a cluster of COVID-19 breakthrough infections after vaccination in Kyamulibwa, Kalungu District, Uganda. All but 1 infection were from SARS-CoV-2 Omicron strain BA.5.2.1. We identified 6 distinct genotypes by genome sequencing. Infections were mild, suggesting vaccination is not protective against infection but may limit disease severity.

SUBMITTER: Mugisha J 

PROVIDER: S-EPMC9796194 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature

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SARS-CoV-2 Omicron BA.5 Infections in Vaccinated Persons, Rural Uganda.

Mugisha Joseph J   Mpairwe Bernard B   Newton Robert R   Cotten Matthew M   Phan My V T MVT  

Emerging infectious diseases 20221218 1

We describe a cluster of COVID-19 breakthrough infections after vaccination in Kyamulibwa, Kalungu District, Uganda. All but 1 infection were from SARS-CoV-2 Omicron strain BA.5.2.1. We identified 6 distinct genotypes by genome sequencing. Infections were mild, suggesting vaccination is not protective against infection but may limit disease severity. ...[more]

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