Ontology highlight
ABSTRACT:
SUBMITTER: D'Elia A
PROVIDER: S-EPMC9800572 | biostudies-literature | 2022 Dec
REPOSITORIES: biostudies-literature
D'Elia Annunziata A Schiavi Sara S Manduca Antonia A Rava Alessandro A Buzzelli Valeria V Ascone Fabrizio F Orsini Tiziana T Putti Sabrina S Soluri Andrea A Galli Filippo F Soluri Alessandro A Mattei Maurizio M Cicconi Rosella R Massari Roberto R Trezza Viviana V
Scientific reports 20221229 1
Autism Spectrum Disorder (ASD) is a pervasive neurodevelopmental disorder emerging in early life characterized by impairments in social interaction, poor verbal and non-verbal communication, and repetitive patterns of behaviors. Among the best-known genetic risk factors for ASD, there are mutations causing the loss of the Fragile X Messenger Ribonucleoprotein 1 (FMRP) leading to Fragile X syndrome (FXS), a common form of inherited intellectual disability and the leading monogenic cause of ASD. B ...[more]