Ontology highlight
ABSTRACT:
SUBMITTER: van Schilfgaarde M
PROVIDER: S-EPMC98391 | biostudies-literature | 2000 Aug
REPOSITORIES: biostudies-literature
van Schilfgaarde M M van Ulsen P P van Der Steeg W W Winter V V Eijk P P Everts V V Dankert J J van Alphen L L
Infection and immunity 20000801 8
Haemophilus influenzae penetrates between epithelial cells via an unknown mechanism. A chromosomal library of nonencapsulated H. influenzae strain A960053 DNA was constructed in Escherichia coli DH5alpha to identify bacterial genes contributing to this paracytosis. Two E. coli clones that contained open reading frames (ORFs) homologous to HI0636 to HI0641 of H. influenzae strain Rd and that showed an increased penetration in epithelial cell layers of the human bronchial epithelial cell line NCI- ...[more]