Ontology highlight
ABSTRACT:
SUBMITTER: Yan Y
PROVIDER: S-EPMC9841182 | biostudies-literature | 2023 Jan
REPOSITORIES: biostudies-literature
Yan Yu Y Park Dong Ik DI Horn Anja A Golub Mari M Turck Christoph W CW
Zoological research 20230101 1
Fluoxetine (Prozac™) is the only antidepressant approved by the US Food and Drug Administration (FDA) for the treatment of major depressive disorder (MDD) in children. Despite its considerable efficacy as a selective serotonin reuptake inhibitor, the possible long-term effects of fluoxetine on brain development in children are poorly understood. In the current study, we aimed to delineate molecular mechanisms and protein biomarkers in the brains of juvenile rhesus macaques (<i>Macaca mulatta</i> ...[more]