Red blood cell rheology during a complete blood count: A proof of concept.
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ABSTRACT:
SUBMITTER: Taraconat P
PROVIDER: S-EPMC9882912 | biostudies-literature | 2023
REPOSITORIES: biostudies-literature
Publications
Red blood cell rheology during a complete blood count: A proof of concept.
Taraconat Pierre P Gineys Jean-Philippe JP Isebe Damien D Nicoud Franck F Mendez Simon S
PloS one 20230127 1
Counting and sizing blood cells in hematological analyzers is achieved using the Coulter principle. The cells flow in a micro-aperture in which a strong electrical field is imposed, so that an electrical perturbation, called pulse, is measured each time a cell crosses the orifice. The pulses are expected to contain information on the shape and deformability of Red Blood Cells (RBCs), since recent studies state that RBCs rotate and deform in the micro-orifice. By implementing a dedicated numerica ...[more]
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