Ontology highlight
ABSTRACT:
SUBMITTER: Ghaedrahmati F
PROVIDER: S-EPMC9926962 | biostudies-literature | 2023 Feb
REPOSITORIES: biostudies-literature
Ghaedrahmati Farhoodeh F Esmaeil Nafiseh N Abbaspour Maryam M
Cancer communications (London, England) 20221230 2
Natural killer (NK) cells are unique innate immune cells that mediate anti-viral and anti-tumor responses. Thus, they might hold great potential for cancer immunotherapy. NK cell adoptive immunotherapy in humans has shown modest efficacy. In particular, it has failed to demonstrate therapeutic efficiency in the treatment of solid tumors, possibly due in part to the immunosuppressive tumor microenvironment (TME), which reduces NK cell immunotherapy's efficiencies. It is known that immune checkpoi ...[more]