Ontology highlight
ABSTRACT:
SUBMITTER: Park SY
PROVIDER: S-EPMC9981691 | biostudies-literature | 2023 Mar
REPOSITORIES: biostudies-literature
Park Se Yong SY Kim Min Woo MW Kang Ju-Hee JH Jung Hyun Jin HJ Hwang Jung Ho JH Yang Soo Jung SJ Woo Jong Kyu JK Jeon Yoon Y Lee Ho H Yoon Yeo Sung YS Seong Je Kyung JK Oh Seung Hyun SH
Scientific reports 20230302 1
Bioluminescence imaging is useful for non-invasively monitoring inflammatory reactions associated with disease progression, and since NF-κB is a pivotal transcription factor that alters expressions of inflammatory genes, we generated novel NF-κB luciferase reporter (NF-κB-Luc) mice to understand the dynamics of inflammatory responses in whole body, and also in various type of cells by crossing NF-κB-Luc mice with cell-type specific Cre expressing mice (NF-κB-Luc:[Cre]). Bioluminescence intensity ...[more]