Ontology highlight
ABSTRACT:
SUBMITTER: Verbiest M
PROVIDER: S-EPMC9990875 | biostudies-literature | 2023 Feb
REPOSITORIES: biostudies-literature
Verbiest Max M Maksimov Mikhail M Jin Ye Y Anisimova Maria M Gymrek Melissa M Bilgin Sonay Tugce T
Journal of evolutionary biology 20221026 2
Short tandem repeats (STRs) are units of 1-6 bp that repeat in a tandem fashion in DNA. Along with single nucleotide polymorphisms and large structural variations, they are among the major genomic variants underlying genetic, and likely phenotypic, divergence. STRs experience mutation rates that are orders of magnitude higher than other well-studied genotypic variants. Frequent copy number changes result in a wide range of alleles, and provide unique opportunities for modulating complex phenotyp ...[more]