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Electron cryotomography of cryosectioned budding yeast cells


ABSTRACT:

SUBMITTER: Lu Gan 

PROVIDER: EMPIAR-10062 | biostudies-other |

REPOSITORIES: biostudies-other

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Publications

Budding yeast chromatin is dispersed in a crowded nucleoplasm in vivo.

Chen Chen C   Lim Hong Hwa HH   Shi Jian J   Tamura Sachiko S   Maeshima Kazuhiro K   Surana Uttam U   Gan Lu L  

Molecular biology of the cell 20160907 21


Chromatin organization has an important role in the regulation of eukaryotic systems. Although recent studies have refined the three-dimensional models of chromatin organization with high resolution at the genome sequence level, little is known about how the most fundamental units of chromatin-nucleosomes-are positioned in three dimensions in vivo. Here we use electron cryotomography to study chromatin organization in the budding yeast Saccharomyces cerevisiae Direct visualization of yeast nucle  ...[more]

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