Cryo-EM structure of TMV with Ca2+ at low pH
Ontology highlight
ABSTRACT:
SUBMITTER: Felix Weis
PROVIDER: EMPIAR-10306 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
Elucidation of the viral disassembly switch of tobacco mosaic virus.
Weis Felix F Beckers Maximilian M von der Hocht Iris I Sachse Carsten C
EMBO reports 20190919 11
Stable capsid structures of viruses protect viral RNA while they also require controlled disassembly for releasing the viral genome in the host cell. A detailed understanding of viral disassembly processes and the involved structural switches is still lacking. This process has been extensively studied using tobacco mosaic virus (TMV), and carboxylate interactions are assumed to play a critical part in this process. Here, we present two cryo-EM structures of the helical TMV assembly at 2.0 and 1. ...[more]
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