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Human apo ferritin frozen on TEM grid with amorphous carbon supporting film

ABSTRACT:

SUBMITTER: Fei Sun

PROVIDER: EMPIAR-10405 | biostudies-other |

REPOSITORIES: biostudies-other

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Publications

Amorphous nickel titanium alloy film: A new choice for cryo electron microscopy sample preparation.

Huang Xiaojun X Huang Xiaojun X Zhang Lei L Wen Zuoling Z Chen Hui H Li Shuoguo S Ji Gang G Yin Chang-Cheng CC Sun Fei F

Progress in biophysics and molecular biology 20200803

Cryo-electron microscopy (cryoEM) has become one of the most important approach for structural biology. However, barriers are still there for an increased successful rate, a better resolution and improved efficiency from sample preparation, data collection to image processing. CryoEM sample preparation is one of the bottlenecks with many efforts made recently, including the optimization of supporting substrate (e.g. ultra-thin carbon, graphene, pure gold, 2d crystal of streptavidin, and affinity ...[more]

PMID: 32758492

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