Dataset Information
Soft X-ray Tomography of mock-infected U2OS cells
Ontology highlight
ABSTRACT:
SUBMITTER: Maria Harkiolaki
PROVIDER: EMPIAR-10413 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
3D Correlative Cryo-Structured Illumination Fluorescence and Soft X-ray Microscopy Elucidates Reovirus Intracellular Release Pathway.
Cell 20200630 2
Imaging of biological matter across resolution scales entails the challenge of preserving the direct and unambiguous correlation of subject features from the macroscopic to the microscopic level. Here, we present a correlative imaging platform developed specifically for imaging cells in 3D under cryogenic conditions by using X-rays and visible light. Rapid cryo-preservation of biological specimens is the current gold standard in sample preparation for ultrastructural analysis in X-ray imaging. H ...[more]