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Soft X-ray Tomography of mock-infected U2OS cells


ABSTRACT:

SUBMITTER: Maria Harkiolaki 

PROVIDER: EMPIAR-10415 | biostudies-other |

REPOSITORIES: biostudies-other

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Imaging of biological matter across resolution scales entails the challenge of preserving the direct and unambiguous correlation of subject features from the macroscopic to the microscopic level. Here, we present a correlative imaging platform developed specifically for imaging cells in 3D under cryogenic conditions by using X-rays and visible light. Rapid cryo-preservation of biological specimens is the current gold standard in sample preparation for ultrastructural analysis in X-ray imaging. H  ...[more]

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