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2.05 angstrom resolution structure determination of sulfur oxygenase reductase using 200kV cryo-EM

ABSTRACT:

SUBMITTER: Naruhiko Adachi

PROVIDER: EMPIAR-10546 | biostudies-other |

REPOSITORIES: biostudies-other

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Crystallographic and cryogenic electron microscopic structures and enzymatic characterization of sulfur oxygenase reductase from <i>Sulfurisphaera tokodaii</i>.

Sato Yuta Y Yabuki Takashi T Adachi Naruhiko N Moriya Toshio T Arakawa Takatoshi T Kawasaki Masato M Yamada Chihaya C Senda Toshiya T Fushinobu Shinya S Wakagi Takayoshi T

Journal of structural biology: X 20200703

Sulfur oxygenase reductases (SORs) are present in thermophilic and mesophilic archaea and bacteria, and catalyze oxygen-dependent oxygenation and disproportionation of elemental sulfur. SOR has a hollow, spherical homo-24-mer structure and reactions take place at active sites inside the chamber. The crystal structures of SORs from <i>Acidianus</i> species have been reported. However, the states of the active site components (mononuclear iron and cysteines) and the entry and exit paths of the sub ...[more]

PMID: 32775998

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