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Jack bean urease imaged at 39kX nominal magnification

ABSTRACT:

SUBMITTER: J. Christopher Fromme

PROVIDER: EMPIAR-10549 | biostudies-other |

REPOSITORIES: biostudies-other

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Experimental evaluation of super-resolution imaging and magnification choice in single-particle cryo-EM.

Feathers J Ryan JR Spoth Katherine A KA Fromme J Christopher JC

Journal of structural biology: X 20210313

The resolution of cryo-EM reconstructions is fundamentally limited by the Nyquist frequency, which is half the sampling frequency of the detector and depends upon the magnification used. In principle, super-resolution imaging should enable reconstructions to surpass the physical Nyquist limit by increasing sampling frequency, yet there are few reports of reconstructions that do so. Here we directly examine the contribution of super-resolution information, obtained with the K3 direct electron det ...[more]

PMID: 33817625

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The nickel ion environment in jack bean urease.

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Sulfonamide-Linked Ciprofloxacin, Sulfadiazine and Amantadine Derivatives as a Novel Class of Inhibitors of Jack Bean Urease; Synthesis, Kinetic Mechanism and Molecular Docking.

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