Cryo electron micrographs of Tetrahymena thermophila solubilized mitochondrial membrane complexes - Glacios data
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ABSTRACT:
SUBMITTER: James Anthony Letts
PROVIDER: EMPIAR-10882 | biostudies-other |
REPOSITORIES: biostudies-other
Publications
Structures of <i>Tetrahymena</i>'s respiratory chain reveal the diversity of eukaryotic core metabolism.
Zhou Long L Maldonado María M Padavannil Abhilash A Guo Fei F Letts James A JA
Science (New York, N.Y.) 20220331 6595
Respiration is a core biological energy-converting process whose last steps are carried out by a chain of multisubunit complexes in the inner mitochondrial membrane. To probe the functional and structural diversity of eukaryotic respiration, we examined the respiratory chain of the ciliate <i>Tetrahymena thermophila</i> (Tt). Using cryo-electron microscopy on a mixed sample, we solved structures of a supercomplex between Tt complex I (Tt-CI) and Tt-CIII<sub>2</sub> (Tt-SC I+III<sub>2</sub>) and ...[more]
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