Ontology highlight
ABSTRACT:
SUBMITTER: Sean Robert Connell
PROVIDER: EMPIAR-11218 | biostudies-other |
REPOSITORIES: biostudies-other
Schedlbauer Andreas A Iturrioz Idoia I Ochoa-Lizarralde Borja B Diercks Tammo T López-Alonso Jorge Pedro JP Lavin José Luis JL Kaminishi Tatsuya T Çapuni Retina R Dhimole Neha N de Astigarraga Elisa E Gil-Carton David D Fucini Paola P Connell Sean R SR
Science advances 20210604 23
While a structural description of the molecular mechanisms guiding ribosome assembly in eukaryotic systems is emerging, bacteria use an unrelated core set of assembly factors for which high-resolution structural information is still missing. To address this, we used single-particle cryo-electron microscopy to visualize the effects of bacterial ribosome assembly factors RimP, RbfA, RsmA, and RsgA on the conformational landscape of the 30<i>S</i> ribosomal subunit and obtained eight snapshots repr ...[more]