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Cryo electron microscopy of assemblies based on truncated PVY coat protein

ABSTRACT:

SUBMITTER: Luka Kavcic

PROVIDER: EMPIAR-11548 | biostudies-other |

REPOSITORIES: biostudies-other

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From structural polymorphism to structural metamorphosis of the coat protein of flexuous filamentous potato virus Y.

Kavčič Luka L Kežar Andreja A Koritnik Neža N Žnidarič Magda Tušek MT Klobučar Tajda T Vičič Žiga Ž Merzel Franci F Holden Ellie E Benesch Justin L P JLP Podobnik Marjetka M

Communications chemistry 20240117 1

The structural diversity and tunability of the capsid proteins (CPs) of various icosahedral and rod-shaped viruses have been well studied and exploited in the development of smart hybrid nanoparticles. However, the potential of CPs of the wide-spread flexuous filamentous plant viruses remains to be explored. Here, we show that we can control the shape, size, RNA encapsidation ability, symmetry, stability and surface functionalization of nanoparticles through structure-based design of CP from pot ...[more]

PMID: 38233506

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